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Science & ResearchJul 24, 2026

Microglia extract neuronal proteolytic organelles via skoupocytosis

Neurons face unique challenges in maintaining protein homeostasis due to their tortuous morphology and extended processes.

Neurons face unique challenges in maintaining protein homeostasis due to their tortuous morphology and extended processes. Proteolytic organelles are typically transported retrogradely towards their soma for degradation where lysosomes are enriched, but some organelles are…

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