Science & ResearchAug 3, 2026
Co-option of retrotransposons promotes antibody diversification.
Activation-induced cytidine deaminase (AID) accomplishes somatic hypermutation (SHM) of V H (D)J H genes in germinal center B cells for antibody diversification and affinity maturation.
Activation-induced cytidine deaminase (AID) accomplishes somatic hypermutation (SHM) of V H (D)J H genes in germinal center B cells for antibody diversification and affinity maturation. How AID specifically targets V H (D)J H remains unclear. We report the discovery of LINE-1…
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