Science & ResearchAug 12, 2026
In vivo genome-wide CRISPR screens of human T cells in solid tumours.
Large-scale CRISPR screening in human T cells holds significant promise for identifying genetic modifications that enhance cellular immunotherapy.
Large-scale CRISPR screening in human T cells holds significant promise for identifying genetic modifications that enhance cellular immunotherapy. Yet, many regulators of T cell performance in solid tumours are not revealed in vitro 1,2 . In vivo screening in tumour-bearing mice…
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