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Science & ResearchJul 20, 2026

Stressor identity shapes plasma proteomic and metabolic responses in humans

Acute stress triggers rapid physiological adaptations, yet how distinct stress modalities shape the human circulating molecular landscape remains unclear.

Acute stress triggers rapid physiological adaptations, yet how distinct stress modalities shape the human circulating molecular landscape remains unclear. We performed longitudinal deep plasma proteomics and targeted metabolomics across three paradigms: psychological stress,…

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