Science & ResearchAug 15, 2026
Location-dependent proteomics of the aorta reveal an atherosclerotic disease gradient shaped by hemodynamics
Background and aims: Atherosclerotic plaques form preferentially at vascular sites exposed to disturbed blood flow, yet the protein changes underlying this site-specific plaque development remain unclear.
Background and aims: Atherosclerotic plaques form preferentially at vascular sites exposed to disturbed blood flow, yet the protein changes underlying this site-specific plaque development remain unclear. Mouse models are widely used to study atherosclerosis but yield only…
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